Open PhD positions

Every position below is supervised by an iMOL principal investigator and connects advanced microscopy with quantitative image analysis. Each project has its own page with the scientific background, the tasks and the profile we are looking for. Positions are offered in two ways: as part of the structured third cohort, which has one application deadline for all projects, and as individual positions in an iMOL group, which are filled as suitable candidates apply.
Third cohort of the Research Training Group
Start 1 March 2027  ·  Application deadline 15 November 2026  ·  E13 TV-G-U, 65 %, 36 months
Super-Resolution Microscopy for Optical Cell Biology
Super-Resolution
Single-Molecule
DNA-PAINT
Image Analysis
Develop new experimental super-resolution microscopy methods for optical cell biology, together with computational tools that turn single-molecule data into quantitative biological information.
👤 PI: Prof. Heilemann
📅 36 months
View full project →
Further cohort projects are published here as they are released. To apply, send one PDF containing a cover letter that names the project or projects you are applying for, your CV, your transcripts and the names of two referees, by 15 November 2026 to imol.coordinator@biophysik.org, or directly to the contact named on the project page.
Positions in the Frangakis group
Reviewed on a rolling basis, independently of the cohort deadline  ·  Starting date by arrangement  ·  E13 TV-G-U, 65 %, 36 months
Structural Analysis of the Kidney Slit Diaphragm
Cryo-ET
FIB-Milling
Kidney Disease
Drosophila · Zebrafish
Resolve the molecular architecture of the glomerular filtration barrier in disease models of FSGS and minimal change disease using in-situ cryo-electron tomography and CLEM.
👤 PI: Prof. Frangakis
📅 36 months
⏱ Rolling
View full project →
Adherens Junctions in Drosophila by Cryo-EM
Cryo-ET
Volume EM
Cytoskeleton
MD Simulations
Study the 4D structural remodelling of cell–cell junctions during dorsal closure in Drosophila using serial-section TEM, FIB-SEM, and molecular dynamics simulations.
👤 PI: Prof. Frangakis
📅 36 months
⏱ Rolling
View full project →
Applications for these two projects are reviewed as they arrive. Please send one PDF containing a cover letter that names the project you are applying for, your CV, your transcripts and the names of two referees to achilleas.frangakis@biophysik.org.
Goethe University is committed to equal opportunity, family friendliness and diversity. Applications from people with a migration background and from other underrepresented groups are particularly welcome. Applicants with a severe disability or equivalent status will be given preference in cases of equal suitability. Costs arising from the application process cannot be reimbursed.
Data protection: personal data contained in your application are processed solely for the purpose of the selection procedure (Art. 88 GDPR in conjunction with § 23 HDSIG) and are not kept longer than required for the procedure and any related legal claims. Details are provided in the privacy policy of Goethe University Frankfurt.