Prof. Dr. Franziska Matthäus

Giersch-Professor for Bioinformatics

Frankfurt Institute for Advanced Studies, Goethe-University Frankfurt, Frankfurt am Main


Research Positions

Junior Professorship, Center for Computational and Theoretical Biology, Würzburg University

Leader of the junior research group “Complex biological systems” at the Center for Modeling and Simulation in the Biosciences (BIOMS) of the University of Heidelberg

Postdoc at BIOMS, University of Heidelberg

Postdoc in the International Graduate School Complex Processes: Modeling, Simulation and Optimization of the Interdisciplinary Center for Scientific Computing (IWR), University of Heidelberg


Honors and Awards

WIN-Fellow of the Heidelberg Academy of Sciences


Scholarship of the Humboldt-University within the exchange program with the Warsaw University

Scholarship by GFPS Polska

Scholarship of the Friedrich-Naumann-Foundation


Selected papers

1. Interacting signalling and cellular waves pattern the feather array. W.K.W. Ho, L. Freem, D. Zhao, M.J. McGrew, K.J. Painter, T. Woolley, E. A. Gaffney, A. Tzika, M. Milinkovitch, P. Schneider, A. Drusko, F. Matthäus, J.L. Glover, H.M. Sang, M.G. Davey, K.L. Wells, J.A. Johansson, M. Clinton, D.J. Headon. PLoS Biology 2019, 17 (2), e3000132.

2. Hierarchical patterning modes orchestrate hair follicle morphogenesis. J.D. Glover, K.L. Wells, F. Matthäus, K.J. Painter, W. Ho, J. Riddell, J.A. Johansson, M. Ford, C.A.B. Jahoda, V. Klika, R.L. Mort, and D.J. Headon. PLoS Biology 2017, 15(7):e2002117.

3. An individual-based model for the collective cancer cell migration explains speed dynamics and phenotype variability in response to growth factors. D. Stichel, A.M. Middleton, B.F. Müller, S. Depner, U. Klingmüller, K. Breuhahn, F. Matthäus. NPJ Systems Biology and Applications 2017, 3, Art. no. 5,  DOI:10.1038/s41540-017-0006-3.

4. TCCA: An R package for the identification of differentially expressed genes in time course microarray data. M. Albrecht, D. Stichel, B.F. Müller, R. Merkle, C. Sticht, N. Gretz, U. Klingmüller, K. Breuhahn, F. Matthäus. BMC Bioinformatics 2017, 18:33. 

5. Concomitant expression of far upstream element (FUSE) binding protein (FBP) interacting repressor (FIR) and its splice variants induce migration and invasion of non-small cell lung cancer (NSCLC) cells. B. Müller*, M. Bovet*, Y. Yin*, D. Stichel*, M. Malz, A.M. Middleton, V. Ehemann, J. Schmitt, T. Muley, M. Meister, E. Herpel, S. Singer, A. Warth, P. Schirmacher, D. Drasdo$, F. Matthäus$, K. Breuhahn$.  J Pathol 2015,  237:390-401.

6. Stathmin regulates keratinocyte proliferation and migration during cutaneous regeneration. S. Schmitt, K. Safferling, K. Westphal, M. Hrabowski, U. Müller, P. Angel, L. Wiechert, V. Ehemann, B. Müller, S. Holland-Cunz, D. Stichel, N. Harder, K. Rohr, G. Germann, F. Matthäus, P. Schirmacher, N. Grabe, K. Breuhahn. PLoS One 2013, 8(9): e75075.

7. Effects of age on the structure of functional connectivity networks during episodic and working memory demand. F. Matthäus, J.-P. Schmidt, A. Banerjee, T.G. Schulze, T. Demirakca, C. Diener. Brain Connectivity 2012, 2(3), DOI: 10.1089/brain.2012.0077.

8. On the origin and characteristics of noise-induced Lévy walks of E. coli. F. Matthäus, M.S. Mommer, T. Curk, J. Dobnikar. PLoS One 2011, 6(4):e18623.

9. E. coli superdiffusion and chemotaxis – search strategy, precision and motility. F. Matthäus, M. Jagodi?, J. Dobnikar. Biophys J 2009, 97(4): 946-957.