Project C3: Analysis of cell motility and cell-cell interactions for multicellular systems

Franziska Matthäus

Work package 1: Approaches for quantitative analyses of collective cell migration

Work package 2: Quantification of cell deformations

Work package 3: Estimation of forces based on deformations and cell motion


Quantitative analysis of collective migration

3D PIV (correlation-based)

Velocity fields from consecutive images

Shape analysis: Segmentation, Skeletonization, representation as polygon, polyeder or scutoid

Estimation of mechanical parameters from cell deformation in epithelial tissues