24 June 2024
Congratulations Johanna !!
Johanna Rahm from the Heilemann group completed her project on the exploring the application of deep learning in super-resolution microscopy and successfully defended her PhD thesis on 24 June 2024. Well done!
Johanna Rahm (center) with her supervisor Mike Heilemann (left) and iMOL speaker Achilleas Frangakis (right).
Smiles all round. In her hands Johanna holds the decorated symbolic doctor’s hat prepared by her colleagues, a German tradition (photos by T. Schuler).
A close-up of Johannas Doktorhut.
1 March 2024
iMOL Research Training Group started on 1st March 2024 with the 2nd cohort of phd students
A part of the new PhD students had the opportunity to attend the Winter School in February 2024.
21 February 2024
Third iMOL winter school retreat in the Alps
The group of iMOL PhD students has doubled in size since the last retreat. The newcomers got to know everybody and their projects, the retreat providing an ideal opportunity for exchange. Again a full programme of talks including invited guest scientists and all iMOL PhD students. A little time was left for outdoor activities though.
24 February 2023
Second iMOL winter school retreat in the Alps
Despite a full schedule of talks by the invited guest scientists and the iMOL PhD students, there was time for joint activities, enjoying the beautiful landscape of the Kleinwalsertal.
29 September 2022
Poster prizes for the Matthäus group at the European Conference for Mathematical and Theoretical Biology
iMOL is proud to announce that PhD students of the Matthäus group have been awarded prizes at this year’s ECMTB 2022 in Heidelberg, a major conference with 750 participants. Marc Pereyra received the Lewis Wolpert Best Poster award. This prize is awarded annually for outstanding contributions to the field of theoretical biology. Marc’s poster can be viewed here. Zoë Lange won the ECMTB award for the best poster in developmental biology’. Her poster can be viewed here. Gustavo Hernandez-Mejia’s received the ECMTB award for the best poster in epidemiology. His poster can be viewed here.
The happy awardees: Marc Pereyra (left), Gustavo Hernandez-Mejia (center) and Zoë Lange (right) (photo by Camile Fraga Delfino Kunz)
28 September 2022
Fast DNA-PAINT imaging using a deep neural network
The advent of super-resolution imaging has overcome the diffraction-limited barrier of light microscopy into obtaining images at nanometre spatial resolution. DNA-PAINT (short for “DNA points accumulation for imaging in nanoscale topography”) is a super-resolution technique with relatively easy-to-implement multi-target imaging. However, image acquisition is slow as sufficient statistical data has to be generated from spatio-temporally isolated single emitters. iMOL scientists and colleagues have trained the neural network DeepSTORM to predict fluorophore positions from high emitter density DNA-PAINT data. They report in the journal Nature Communications that they achieved this way image acquisition in one minute. They demonstrate multi-colour super-resolution imaging of structure-conserved semi-thin neuronal tissue and imaging of large samples. This improvement can be integrated into any single-molecule imaging modality to enable fast single-molecule super-resolution microscopy.
Research paper: Kaarjel Narayanasamy, Johanna Rahm, Siddharth Tourani and Mike Heilemann (2022) Fast DNA-PAINT imaging using a deep neural network. Nature Communications 13: 5047. Link
Contact: Mike Heilemann, Institute of Physical and Theoretical Chemistry, Goethe University, Frankfurt/Main, heileman@chemie.uni-frankfurt.de
19 September 2022
Utz Ermel from the Frangakis group received the award for best poster at the 9th Electron Tomography Congress
iMOL is proud to announce that Utz from the Frangakis group won the award for the best poster at the 9th Electron Tomography Congress, 11 to 14 September 2022 in Egmond aan Zee in the Netherlands.
25 February 2022
First iMOL winter school retreat in the Alps
Despite a full schedule of interesting talks by the invited guest scientists, the iMOL PIs and the iMOL PhD students, there was time for joint activities, enjoying the beautiful winter landscape of the Kleinwalsertal.
1 March 2021