Prof. Dr. Ernst H.K. Stelzer

Professor for Physical Biology, Goethe-University, Frankfurt/Main

Dean for academic studies of the Faculty of Biosciences at Goethe-University, Frankfurt/Main

Director of the Frankfurt Center for Advanced Light Microscopy of Goethe-University, BMLS, Goethe-University, Frankfurt/Main


Research Positions

Cluster of Excellence Frankfurt/Main – Macromolecular Complexes

Open-ended contract at EMBL in Cell Biology & Biophysics Unit

Scientific Group Leader at EMBL Heidelberg in Cell Biophysics Programme as well as in Cell Biology Programme

Project Leader at EMBL, Heidelberg, Physical Instrumentation Programme

Assistent at Max-Planck-Institut für Biophysik, Frankfurt/Main


Honors and Awards

The Lennart Philipson Award 2016, awarded by European Molecular Biology Laboratory (EMBL, Heidelberg, Germany)

Honorary Fellow of the Royal Microscopical Society (RMS, Oxford, UK)

Carl Zeiss Lecture 2014, awarded by The German Society for Cell Biology (DGZ)

Boris Balinsky Life Sciences Lecture, awarded by The Microscopy Society of Southern Africa, Cape Town, South Africa

HMLS Investigator Award 2009, awarded by Heidelberg Molecular Life Sciences (Faculties of Biosciences and Medicine, University of Heidelberg, DKFZ, EMBL, MPI-mF)

EMBO Member European Molecular Biology Organisation (Heidelberg, Germany)

Ernst Abbe Lecture 1999, awarded by the Royal Microscopical Society (RMS, Oxford, UK) and Carl Zeiss (Jena/Oberkochen), Heidelberg


Selected papers

1. A universal vector concept for a direct genotyping of transgenic organisms and a systematic creation of homozygous lines. Strobl F, Anderl A, Stelzer EHK. eLife 2018, 7:e31677. doi: 10.7554/eLife.31677.

2. Oocyte DNA damage quality control requires consecutive interplay of CHK2 and CK1 to activate p63. Tuppi M, Kehrloesser S, Coutandin DW, Rossi V, Luh LM, Strubel A, Hötte K, Hoffmeister M, Schäfer B, De Oliveira T, Greten F, Stelzer EHK, Knapp S, De Feliciv M, Behrends C, Klinger FG, Dötsch V. Nature Structural & Molecular Biology 2018, volume 25, p 261–269. doi:10.1038/s41594-018-0035-7.

3. csiLSFM combines light-sheet fluorescence microscopy and coherent structured illumination for a lateral resolution below 100 nm. Chang BJ, Perez Meza VD, Stelzer EHK. PNAS 2017, 114(19):4869-4874.

4. Rules and Self-Organizing Properties of Post-embryonic Plant Organ Cell Division Patterns, von Wangenheim D, Fangerau J, Schmitz A, Smith RS, Leitte H, Stelzer EHK, Maizel A. Current Biology 2016, 26:1–11.

5. Live imaging of Tribolium castaneum embryonic development using light-sheet–based fluorescence microscopy. Strobl F, Schmitz A, Stelzer EHK. Nature Protocols 2015, 10:1486.1507.

6. Light-sheet fluorescence microscopy for quantitative biology. Stelzer EHK. Nature Methods 2015, 12(1):23–27.

7. Fast, high-contrast imaging of animal development with scanned light sheet-based structured-illumination microscopy. Keller PJ, Schmidt AD, Santella A, Khairy K, Bao Z, Wittbrodt J, Stelzer EHK. Nature Methods 2010, 7(8):637-642.

8. The third dimension bridges the gap between cell culture and live tissue. Pampaloni F, Reynaud EG, Stelzer EHK. Nature Reviews Molecular Cell Biology 2007, 8(10):839-845.

9. Reconstruction of zebrafish early embryonic development by Scanned Light Sheet Microscopy. Keller PJ, Schmidt AD, Wittbrodt J, Stelzer EHK. Science 2008, 322(5904):1065-1069.

10. Optical sectioning deep inside live embryos by selective plane illumination microscopy. Huisken J, Swoger J, Del Bene F, Wittbrodt J, Stelzer EHK. Science 2004, 305:1007-1009.